The Center for Biomolecular NMR Spectroscopy offers state-of-the-art high field NMR instrumentation for structural studies of biological macromolecules. The instrumentation presently available includes four-channel Bruker Avance 500, 600, and 700 MHz NMR spectrometers. The facility also has available an ultrahigh sensitivity 5mm 1H-13C-15N triple-resonance cold probe for the 600 MHz spectrometers. The resources of the facility can be accessed either on a fee-for-service or on a collaborative use basis. The types of analyses conducted on a fee-for-service basis include acquisition and analysis of the required spectra for the elucidation of small molecule structures (includes synthetic molecules, natural products, cofactors, lipids, and short peptides (30 amino acids or less)). The types of projects conducted collaboratively include the determination of three-dimensional structures of biological macromolecules, including proteins and nucleic acids, both alone and as complexes with various ligands. The instrumentation available in the Center was purchased through funds provided by the NIH National Center for Research Resources, the Houston Endowment, the UT Health San Antonio Children’s Cancer Research Center, and the U. Texas Permanant University Fund (see Facility History). The operational costs of the facility are supported by the Macromolecular Shared Resource of the Cancer Therapy & Research Center (CTRC), the UT Health San Antonio Core Facilities Committee, and User Fees.

NMR Core Director

Dmitri Ivanov
Asst. Professor
Department Biochemistry
Research Administration Building, Room 5.210
Tel: 210-567-8781
ivanov@uthscsa.edu

 

 

 

NMR Core Technical Director

Kristin E. Cano
Department Biochemistry
Research Administration Building, Room 5.210
Tel: (210) 567-8706
canok@uthscsa.edu

Location

Research Administration Building 5.206

 Contacts

NMR Facility 210-567-8791
NMR Facility 210-567-8789
NMR Linux Workstation Cluster 210-567-8742