{"id":563,"date":"2024-12-04T10:12:09","date_gmt":"2024-12-04T16:12:09","guid":{"rendered":"https:\/\/wp.uthscsa.edu\/cio\/?page_id=563"},"modified":"2026-10-02T13:51:02","modified_gmt":"2026-10-02T18:51:02","slug":"cancer-prevention-strategies","status":"publish","type":"page","link":"https:\/\/wp.uthscsa.edu\/cio\/research\/cancer-prevention-strategies\/","title":{"rendered":"Development of Novel Cancer Prevention Strategies"},"content":{"rendered":"<div class=\"wpb-content-wrapper\" id=\"wpb-content-root\"><p>[vc_row][vc_column width=&#8221;2\/3&#8243;][vc_column_text]<span data-contrast=\"auto\">Researchers at the CIO use induced pluripotent stem cell (iPSC) technologies to studying tumor precursors and develop models of early carcinogenesis. By selecting iPSC lines from patients across the spectrum of genetic cancer risk, researchers are asking how inherited genetic variants cause cancer predisposition by developing patient avatars of early tumor formation. Those avatars can then be used to identify early-stage biomarkers, or test novel cancer prevention drugs.\u00a0<\/span><span data-ccp-props=\"{}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"auto\">Our translational research activities are focused on targeted surgical prevention. For the most common ovarian cancer subtype, surgical removal of fallopian tubes (salpingectomy) can massively reduce a patients risk of ovarian cancer later in life. CIO projects are identifying creative ways to maximize uptake of salpingectomy, particularly in Hispanic women who have been under-represented in ovarian cancer prevention studies to date.<\/span><span data-ccp-props=\"{}\">\u00a0<\/span>[\/vc_column_text][vc_row_inner][vc_column_inner][\/vc_column_inner][\/vc_row_inner][\/vc_column][vc_column width=&#8221;1\/3&#8243;]<nav id=\"subnav\" class=\"callout outline\" aria-label=\"Sub navigation for Research Subnav\"><ul id=\"menu-research-subnav\" class=\"subnav vertical menu drilldown\" data-drilldown><li id=\"menu-item-488\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-488\"><a href=\"https:\/\/wp.uthscsa.edu\/cio\/research\/\">Research<\/a><\/li>\n<li id=\"menu-item-491\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-491\"><a href=\"https:\/\/wp.uthscsa.edu\/cio\/membership\/current-members\/\">Current Members<\/a><\/li>\n<li id=\"menu-item-489\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-489\"><a href=\"https:\/\/wp.uthscsa.edu\/cio\/research\/seminars\/\">Seminar Series<\/a><\/li>\n<li id=\"menu-item-490\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-490\"><a href=\"https:\/\/wp.uthscsa.edu\/cio\/research\/publications\/\">Publications<\/a><\/li>\n<li id=\"menu-item-523\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-523\"><a href=\"https:\/\/wp.uthscsa.edu\/cio\/contact-us\/\">Contact Us<\/a><\/li>\n<\/ul><\/nav>[\/vc_column][\/vc_row][vc_row][vc_column][vc_column_text]\n<table id=\"tablepress-13\" class=\"tablepress tablepress-id-13\">\n<thead>\n<tr class=\"row-1\">\n\t<th class=\"column-1\">Funding<\/th><th class=\"column-2\">Grant Title<\/th><th class=\"column-3\">Publication<\/th>\n<\/tr>\n<\/thead>\n<tbody class=\"row-striping row-hover\">\n<tr class=\"row-2\">\n\t<td class=\"column-1\">CPRIT; RP260516<\/td><td class=\"column-2\">Improving Access to Risk-Reducing Opportunistic-Salpingectomies in South Texas Women<\/td><td class=\"column-3\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/34965417\/\" target=\"_blank\">PMID: 34965417<\/a><\/td>\n<\/tr>\n<tr class=\"row-3\">\n\t<td class=\"column-1\">CPRIT; RR230078<\/td><td class=\"column-2\">Recruitment of Established Investigator Award<\/td><td class=\"column-3\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40301634\/\" target=\"_blank\">PMID: 40301634<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<!-- #tablepress-13 from cache -->[\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>[vc_row][vc_column width=&#8221;2\/3&#8243;][vc_column_text]Researchers at the CIO use induced pluripotent stem cell (iPSC) technologies to studying tumor precursors and develop models of early carcinogenesis. By selecting iPSC lines from patients across the spectrum of genetic cancer risk, researchers are asking how inherited genetic variants cause cancer predisposition by developing patient avatars of early tumor formation. Those avatars [&hellip;]<\/p>\n","protected":false},"author":326,"featured_media":0,"parent":416,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-563","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Development of Novel Cancer Prevention Strategies - Center for Inherited Oncogenesis<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/wp.uthscsa.edu\/cio\/research\/cancer-prevention-strategies\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Development of Novel Cancer Prevention Strategies - Center for Inherited Oncogenesis\" \/>\n<meta property=\"og:description\" content=\"[vc_row][vc_column width=&#8221;2\/3&#8243;][vc_column_text]Researchers at the CIO use induced pluripotent stem cell (iPSC) technologies to studying tumor precursors and develop models of early carcinogenesis. By selecting iPSC lines from patients across the spectrum of genetic cancer risk, researchers are asking how inherited genetic variants cause cancer predisposition by developing patient avatars of early tumor formation. Those avatars [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/wp.uthscsa.edu\/cio\/research\/cancer-prevention-strategies\/\" \/>\n<meta property=\"og:site_name\" content=\"Center for Inherited Oncogenesis\" \/>\n<meta property=\"article:modified_time\" content=\"2026-10-02T18:51:02+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/wp.uthscsa.edu\\\/cio\\\/research\\\/cancer-prevention-strategies\\\/\",\"url\":\"https:\\\/\\\/wp.uthscsa.edu\\\/cio\\\/research\\\/cancer-prevention-strategies\\\/\",\"name\":\"Development of Novel Cancer Prevention Strategies - Center for Inherited Oncogenesis\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/wp.uthscsa.edu\\\/cio\\\/#website\"},\"datePublished\":\"2024-12-04T16:12:09+00:00\",\"dateModified\":\"2026-10-02T18:51:02+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/wp.uthscsa.edu\\\/cio\\\/research\\\/cancer-prevention-strategies\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/wp.uthscsa.edu\\\/cio\\\/research\\\/cancer-prevention-strategies\\\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/wp.uthscsa.edu\\\/cio\\\/research\\\/cancer-prevention-strategies\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/wp.uthscsa.edu\\\/cio\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Research\",\"item\":\"https:\\\/\\\/wp.uthscsa.edu\\\/cio\\\/research\\\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Development of Novel Cancer Prevention Strategies\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/wp.uthscsa.edu\\\/cio\\\/#website\",\"url\":\"https:\\\/\\\/wp.uthscsa.edu\\\/cio\\\/\",\"name\":\"Center for Inherited Oncogenesis\",\"description\":\"Center for Inherited Oncogenesis\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/wp.uthscsa.edu\\\/cio\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Development of Novel Cancer Prevention Strategies - Center for Inherited Oncogenesis","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/wp.uthscsa.edu\/cio\/research\/cancer-prevention-strategies\/","og_locale":"en_US","og_type":"article","og_title":"Development of Novel Cancer Prevention Strategies - Center for Inherited Oncogenesis","og_description":"[vc_row][vc_column width=&#8221;2\/3&#8243;][vc_column_text]Researchers at the CIO use induced pluripotent stem cell (iPSC) technologies to studying tumor precursors and develop models of early carcinogenesis. By selecting iPSC lines from patients across the spectrum of genetic cancer risk, researchers are asking how inherited genetic variants cause cancer predisposition by developing patient avatars of early tumor formation. Those avatars [&hellip;]","og_url":"https:\/\/wp.uthscsa.edu\/cio\/research\/cancer-prevention-strategies\/","og_site_name":"Center for Inherited Oncogenesis","article_modified_time":"2026-10-02T18:51:02+00:00","twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/wp.uthscsa.edu\/cio\/research\/cancer-prevention-strategies\/","url":"https:\/\/wp.uthscsa.edu\/cio\/research\/cancer-prevention-strategies\/","name":"Development of Novel Cancer Prevention Strategies - Center for Inherited Oncogenesis","isPartOf":{"@id":"https:\/\/wp.uthscsa.edu\/cio\/#website"},"datePublished":"2024-12-04T16:12:09+00:00","dateModified":"2026-10-02T18:51:02+00:00","breadcrumb":{"@id":"https:\/\/wp.uthscsa.edu\/cio\/research\/cancer-prevention-strategies\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/wp.uthscsa.edu\/cio\/research\/cancer-prevention-strategies\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/wp.uthscsa.edu\/cio\/research\/cancer-prevention-strategies\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/wp.uthscsa.edu\/cio\/"},{"@type":"ListItem","position":2,"name":"Research","item":"https:\/\/wp.uthscsa.edu\/cio\/research\/"},{"@type":"ListItem","position":3,"name":"Development of Novel Cancer Prevention Strategies"}]},{"@type":"WebSite","@id":"https:\/\/wp.uthscsa.edu\/cio\/#website","url":"https:\/\/wp.uthscsa.edu\/cio\/","name":"Center for Inherited Oncogenesis","description":"Center for Inherited Oncogenesis","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/wp.uthscsa.edu\/cio\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"}]}},"_links":{"self":[{"href":"https:\/\/wp.uthscsa.edu\/cio\/wp-json\/wp\/v2\/pages\/563","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wp.uthscsa.edu\/cio\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/wp.uthscsa.edu\/cio\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/wp.uthscsa.edu\/cio\/wp-json\/wp\/v2\/users\/326"}],"replies":[{"embeddable":true,"href":"https:\/\/wp.uthscsa.edu\/cio\/wp-json\/wp\/v2\/comments?post=563"}],"version-history":[{"count":1,"href":"https:\/\/wp.uthscsa.edu\/cio\/wp-json\/wp\/v2\/pages\/563\/revisions"}],"predecessor-version":[{"id":819,"href":"https:\/\/wp.uthscsa.edu\/cio\/wp-json\/wp\/v2\/pages\/563\/revisions\/819"}],"up":[{"embeddable":true,"href":"https:\/\/wp.uthscsa.edu\/cio\/wp-json\/wp\/v2\/pages\/416"}],"wp:attachment":[{"href":"https:\/\/wp.uthscsa.edu\/cio\/wp-json\/wp\/v2\/media?parent=563"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}