From the Chairman: Paolo Casali, M.D.

The Department of Microbiology, Immunology & Molecular Genetics (MIMG) is part of the Long School of Medicine at the University of Texas Health Science Center at San Antonio. Our faculty conducts research on the immune system, infectious agents and cancer. Accordingly, the department is the nucleus for research and education in immunological and microbiological topics for the five schools at the University of Texas Health Science Center at San Antonio, and provides a dynamic environment for scientific discovery and training.
Our mission is to further research in molecular immunology, microbial pathogenesis, tumor immunology, autoimmunity, immunodeficiencies and development of the immune system, in order to build the knowledge necessary for vaccines and therapies of the future.  We use molecular genetics and epigenetics approaches in conjunction with next-generation sequencing tools to dissect mechanisms for generations of antibodies and lymphocytes that protect against viruses, bacteria, fungi, as well as tumor cells.  We also strive to understand molecular mechanisms of tumorigenesis, with particular emphasis on B lymphocyte neoplastic transformation in the context of the developing immune system. To this end, basic and translational research are of equal importance, to foster discovery of biological truths and translate those discoveries into new therapeutics.
We are committed to developing the next generation of scientists in biomedical research with an emphasis on molecular immunology, and to this end, we offer a spectrum of training opportunities. We house an Undergraduate Research Program, in addition to a Master of Science Program in Immunology and Infection. Our faculty also teach and mentor PhD students through the Molecular Immunology & Microbiology Discipline of the Integrated Biomedical Science Program in the Graduate School of Biomedical Sciences, in addition to providing the teaching in immunology and infection to our medical students. Finally, in addition to undergraduate and graduate trainees, Postdoctoral Fellows are important in our overall research effort. Postdoctoral fellowships are available in most laboratories of the Department of Microbiology, Immunology & Molecular Genetics.

Learning and Training Opportunities

The Department of Microbiology, Immunology & Molecular Genetics supports a variety of learning and training opportunities in seminars, lectures and events, including

Contact the Program Coordinators at:

NIH T32 Graduate Research in Immunology Program (GRIP)

Dr. Paolo Casali, chairman of the Department of Microbiology, Immunology & Molecular Genetics (MIMG), was awarded a T32 (1 T32 AI138944-01) Training Grant for his Graduate Research in Immunology Program (GRIP) from the National Institutes of Health. The five-year grant began September 1, 2018, and the first eligible graduate students will be selected for the upcoming academic year. Click here for more information.

New Grant Awards

  • Dr. Peter Dube was recently awarded a William and Ella Owens Medical Research Foundation grant “Novel Melanoma Vaccines and Adjuvants”
  • Dr. William Kaiser was recently awarded a William and Ella Owens Medical Research Foundation grant “Treatment of Cancer by Inducing Immunogenic Cell Death”
  • Dr. Alexei Tumanov was recently awarded a William and Ella Owens Medical Research Foundation grant “Novel approach to prevent liver toxicity in immune checkpoint cancer therapy”
  • Dr. David Kadosh was recently awarded NIH R21 grant “Regulation of Protein Synthesis During the C. albicans-Macrophage Interaction”
  • Dr. Paolo Casali was recently awarded a 5-year NIH R01 grant “Intrinsic B cell epigenetic regulation of antibody and autoantibody responses by Sirt1” from NIAID for $2,384,804 total award costs
  • Dr. Guangming Zhong was recently awarded NIH R21 grant “Gut Microbiome and Chlamydia pathogenicity in the upper genital tract”
  • Dr. Nu Zhang was recently awarded an American Cancer Society – Research Scholar Grant “Stroma and T cell interaction controls Tcf1 + CD8 T cells in tumor immunity”
  • Dr. Thirumalai Kannan was recently awarded NIH R01 grant “Unique ADP-ribosylating and vacuolating properties of Mycoplasma pneumoniae CARDS toxin trigger airway inflammation and disease progression”.

Upcoming Deadlines

  • NIH R01 (New applications) – June 5, 2019
  • NIH R21 (New applications) – June 16, 2019
  • NIH R01 (Renewal, Resubmission, Revision applications) – July 5, 2019
  • NIH R21 (Renewal, Resubmission, Revision applications) – July 16, 2019

NIAID Funding Opportunities: Click Here
NCI Funding Opportunities: Click Here
NIGMS Funding Opportunities: Click Here
NIA Funding Opportunities: Click Here
SOM Internal Funding Opportunities: Click Here
Office of Sponsored Programs (OSP): Click Here

Additional Funding Opportunities:

Xiangya Medical Student Research Program

The Xiangya Medical Student Research Program is an opportunity for faculty to recruit and mentor medical students from the Xiangya School of Medicine (Changsha, China).

Students from the Xiangya Medical School are given the opportunity to spend two years away from their home institute of Xiangya to gain hands on research experience in a lab at the UT Health Science Center San Antonio.

MIMG Faculty member, Dr. Guangming Zhong, founded the program in which we now have nearly 30 students from Xiangya working in UT Health SA labs, many of which work in MIMG labs.

Dr. Zhong is currently flanked by Dr. Casali who has been a strong supporter of the program since it’s inception.

Not only is this a wonderful experience for the medical students, but also for our faculty, staff and students who are able to learn about a new culture and expand their collaborative network.