We are members of the Children’s Oncology Group, a national consortium of institutions dedicated to curing cancer in children and adolescents by offering state-of-the-art therapy in the form of clinical trials. We provide comprehensive assessment and treatment in a multidisciplinary fashion in specialized programs:

  • Leukemia & Lymphoma Program
  • Bone & solid tumor Program
  • Neuro-Oncology Program
  • Cancer Genetics and Risk Assessment
  • Developmental Therapeutics
  • Adolescent and Young Adult Program

Furthermore, the division holds a federal grant for the National Cancer Institute Community Oncology Research Program (NCORP), a consortium of five institutions whose mission is to facilitate access to COG and other NCTN clinical trials for minority Children, AYAs affected by cancer.

Bone & Soft Tissue Sarcoma Program

The program provides state-of-the-art clinical care combining the expertise of board-certified physicians from the UT Health San Antonio, UT Kids, and the facilities and resources of the University Healthcare System.

Solid Tumor Program

The patients treated by our team benefit from exclusively board-certified providers who combine the resources of the University Health System with the academic knowledge of the University of Texas Health Science Center at San Antonio.

Childhood Cancer Survivorship Program

Cancers considered incurable 30 years ago, now respond to treatments that produce 80 percent overall survival. This program provides comprehensive care and support for cancer survivors and their families. Our philosophy is that survivors of childhood cancer should be seen once a year, followed for life and well-informed about their health history.

Cancer Genetics and Risk Assessment

Although most cancers and blood diseases do not develop because of an underlying familial tendency, in a small but important percentage of cases, we are able to identify an underlying genetic alteration that may contribute to the disorder.

Pediatric Neuro-Oncology Program

Our Neuro-Oncology program  treats patients with a wide variety of both benign and malignant tumors that arise in the brain and spinal cord.


Our hematology program specializes in caring for children with both common and rare blood disorders.  We offer comprehensive clinical services spanning the spectrum of blood diseases including bleeding and clotting disorders, hemoglobin disorders, marrow failure syndromes such as Diamond-Blackfan Anemia and congenital neutropenia. We use genetic diagnosis and counseling to help families better understand their child’s disease.  Services are provided through various outpatient clinical sites as well as our dedicated inpatient hematology consultation service.  In addition, our providers participate in blood disorders research including both observational and treatment studies.

Our hematology providers include five physicians, a nurse practitioner, two nurse coordinators, a social worker, a psychologist, genetic counselor, and research coordinator:

  • Melissa Frei-Jones, MD, MSCI – Diagnosis and treatment of sickle cell, thalassemia, bleeding and clotting disorders.
  • Donna Doulton, RN – Nurse Coordinator, Sickle Cell Program
  • Chatchawin Assanasen, MD – Complement disorders including the diagnosis and treatment of hemolytic uremic syndrome (HUS/aHUS) and paroxysmal nocturnal hemoglobinuria (PNH)
  • Deanna Maida, MD – General Hematology, bleeding and clotting disorders.
  • Patricia Amerson, PNP – Outpatient treatment and follow-up of bleeding and clotting disorders and other blood disorders.
  • Dezarae Tate, RN – Nurse Coordinator, Hemophilia Treatment Center

South Texas Comprehensive Hemophilia & Thrombophilia Treatment Center

The South Texas Hemophilia & Thrombophilia Treatment Center is a federally funded comprehensive pediatric and adult program for patients with hemophilia, von Willebrand disease, platelet and clotting disorders.  Our comprehensive care includes in addition to medical evaluations, genetic counseling, physical therapy evaluation and treatment as needed, and outreach to the Rio Grande Valley.

South Texas Sickle Cell Center

The Sickle Cell program is dedicated to the evidence based treatment of children, adolescents, and young adults living with sickle cell disease through a comprehensive program aimed at preventing disease complications, promoting health literacy and maximizing quality of life.

To make an appointment with one of our doctors, please call 210-743-2300

Dr. Grimes