Research Projects

  • Metabolomics in health and disease
  • Novel therapies for progressive kidney disease
  • Biomarkers in kidney disease
  • Mitochondrial function and cytokine signaling in kidney disease
  • Vascular injury in obesity and diabetes-related kidney disease
  • Transcription factors involved in glucose toxicity
  • Innovative health care delivery systems for diabetes, obesity and CKD


  • NIDDK, DP3 Award, PI-Sharma, Novel Paradigms in Diabetic Complications
  • NIDDK, SBIR Phase I and Phase II, PI-Sharma of Academic Contract, Company PI-Rychak, Ultrasound mediated targeted delivery for kidney disease, Targeson, Inc. Academic PI 2008-2013
  • VA Merit Grant, PI-Sharma, Adiponectin and Podocytes
  • Paricalcitol and Diabetic Nephropathy, PI-Sharma, Abbott, Investigator Initiated
  • Metabolomics in Diabetic Kidney Disease, PI-Sharma, Innovative Grant, Juvenile Diabetes Research Foundation, Principal Investigator
  • The Genetic Basis of Obesity/Diabetes in Saudi Population, King Abdullah University of Science and Technology (KAUST) PI: Kumar Sharma, Co-PIs: Jerry Olefsky, Kelly Frazer, Trey Ideker
  • Anti-inflammatory treatment in diabetic kidney disease. Janssen Labs, 2012-2013 (PI: Sharma)
  • Atrasentan for diabetic kidney disease. Abbott Labs, (PI: Sharma)